Adaptive Analysis of Diastolic Murmurs for Coronary Artery Disease Based on Empirical Mode Decomposition

Coronary Artery Disease (CAD) is a leading type of heart disease in the world caused by the gradual build-up of plaque on the walls of the arteries. Due to CAD’s high incidence rate and mortality, it is very harmful to human health. CAD can develop slowly and silently over years without any symptoms. Early diagnose of CAD is one of the most important medical research areas. Diastolic murmurs that occur as additional components in the heart sound signal provide clinicians with valuable diagnostic and prognostic information about the function of heart valves. When coronary arteries become narrowed or blocked, the turbulence appears which is produced by blood moving across the stenotic arteries. During the relatively quiet diastolic period of the cardiac cycle, the murmurs are likely to be loudest when coronary blood flow is maximal. Initial studies show that diastolic murmurs produced by coronary arterial stenosis contain higher frequency components.